import boto3

session = boto3.Session(profile_name='slscode')
ec2 = session.resource("ec2")

instances = ec2.instances.filter(Filters=[
    {   
        'Name': 'tag-key',
        'Values': ["Name"],
    },  
    {   
        'Name': 'tag-value',
        'Values': ["my-misbehaving-instance"],
    },  
    {   
        'Name': 'instance-state-name',
        'Values': ["running"],
    },  
])  

if len([i for i in instances]) == 0:
    print("not in `running` state")
else:
    server = [i for i in instances][-1]
    print("Found server %s" % server.instance_id)
    server.reboot()
    print("Rebooted server %s" % server.instance_id)

Found server i-02452bb430f04d158
Rebooted server i-02452bb430f04d158

# subnet subnet-4b36143d
# sg sg-9c50c2e5 named network-WebServerSecurityGroup-16RHZWLDGGOGI
# Amazon Linux AMI ami-643b1972
instance = ec2.create_instances(
    ImageId='ami-a07379d9',
    InstanceType='t2.micro',
    KeyName='hornet-slscode',
    SecurityGroupIds=[
        'sg-9c50c2e5'
    ],
    SubnetId='subnet-4b36143d',
    TagSpecifications=[
        {
            'ResourceType': 'instance',
            'Tags': [
                {
                    'Value': 'my-misbehaving-instance',
                    'Key': 'Name'
                },
                {
                    'Value': 'boto3+ipython',
                    'Key': 'tool'
                }
            ]
        }
    ],
    MinCount=1,
    MaxCount=1
)
instance

[ec2.Instance(id='i-0d98ef415d4bec0fe')]